interaction of cationic phosphorus dendrimers with lipid membranes

نویسندگان

m. ionov

department of general biophysics, university of lodz, banacha 12/16, 90-237, lodz, poland. d. wróbel

department of general biophysics, university of lodz, banacha 12/16, 90-237, lodz, poland. k. gardikis

department of pharmaceutical technology, school of pharmacy university of athens, panepistimiopolis, zografou 15771, athens, greece. s. hatziantoniou

department of pharmaceutical technology, school of pharmacy university of athens, panepistimiopolis, zografou 15771, athens, greece. c. demetzos

چکیده

large unilamellar liposomes and multilamellar vesicles consisting of dmpc interacted with cationic phosphorus-containing dendrimers cpds g3 and g4. dsc and ζ -potential measurements have shown that liposomal-dendrimeric molecular recognition occurs due to the interaction between the complementary surface groups. calorimetric studies indicate that the enthalpy of the transition of the lipids that interact with cpds is dependent on the dendrimers generation. these results can be used in order to rationally design mixed modulatory liposomal locked-in dendrimeric, drug delivery nano systems.

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Interaction of cationic phosphorus dendrimers with lipid membranes

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عنوان ژورنال:
international journal of nano dimension

جلد ۲، شماره Issue ۱، صفحات ۵۵-۶۰

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